Perioperative use of dexmedetomidine in an infant with familial dysautonomia

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Familial dysautonomia.

Familial dysautonomia is a rare syndrome of childhood affecting the nervous system. As the name suggests, dysfunction of the autonomic system is a prominent feature. It was first recognized as a separate entity by Riley, Day, Greeley and Langford (1949), the first large series being described by Riley (1952). So far, about 70 patients have been recorded. Though the fully developed syndrome is u...

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Case scenario: perioperative administration of tocotrienols and green tea extract in a child with familial dysautonomia.

F AMILIAL dysautonomia (FD, also known as Riley-Day syndrome) is a rare (1:3,700 live births) autosomal recessive disorder, largely afflicting those of Ashkenazi Jewish descent. One of five hereditary sensory and autonomic neuropathies (HSAN, type III) influencing the development and survival of varied sensory, sympathetic, and parasympathetic neurons, FD is characterized by profound autonomic ...

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Familial Dysautonomia (FD)

Familial dysautonomia (FD) is an autosomal recessive congenital neuropathy which results from poor development and progressive degeneration of the nervous system. The mutation responsible for FD was found at the 5�ss of intron 20 of the IKBKAP gene, encoding the I?B kinase complex-associated protein (IKAP...

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Familial Dysautonomia (FD)

Familial dysautonomia (FD) is an autosomal recessive congenital neuropathy which results from poor development and progressive degeneration of the nervous system. The mutation responsible for FD was found at the 5�ss of intron 20 of the IKBKAP gene, encoding the I?B kinase complex-associated protein (IKAP...

متن کامل

Familial Dysautonomia (FD)

Familial dysautonomia (FD) is an autosomal recessive congenital neuropathy which results from poor development and progressive degeneration of the nervous system. The mutation responsible for FD was found at the 5�ss of intron 20 of the IKBKAP gene, encoding the I?B kinase complex-associated protein (IKAP...

متن کامل

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2009

ISSN: 0007-0912

DOI: 10.1093/bja/aep178